This is a topic dear to my heart, yet I have a 2007 E350 chassis, hoping to soften our front suspension by soon replacing our stock E350 front coil springs with E150 coil springs.
To you with an E450 2350, as you have determined, your chassis is far over-rated for the actual load it is carrying. The source of your jarring condition is related to an extra stiff, extra capable front and rear suspension. What I share next is what I feel will get you going in the right direction, and it should be a very affordable solution compared to all other options.
Keep in-mind that I am not an authority on all this.
During your next RV trip, fully loaded with a tank full of gasoline, propane, fresh water (no waste water), whatever you typically mount on your rear hitch, all your stuff including clothing, supplies, cookware, food, bottled water, and also you in your typical seating positions inside the RV.........get your rig weighed at a truck stop with a truck weigh scale. Weigh each axle independently as is common practice on those scales. With the weight numbers, you can determine the difference between your actual weight on each axle, and compare those numbers with the capability of each axle. I am NO EXPERT HERE so don't take my word as gospel, but I feel you want your actual load per axle to be 500-750 pounds less than the axle's capability. If the gap is significantly more, your ride will be quite rough as you are experiencing today.
I did that exercise with our 2350. Our front axle is extremely light with an actual load (worst case scenario) of 3260 pounds and a capability of 4600 pounds, a 1140 pound difference. On our heaviest trip ever, our rear axle weighed 8220 pounds on the rear axle that is capable of 7800 pounds, a deficiency (over-load condition) of 420 pounds. Since then we are more mindful of what we carry and where we place the weight.
In your case with model 2350 on an E450 chassis, you won't have a rear axle over-load condition, but rather a severe under-load condition like I have with my front axle. As I previously mentioned, I will soon swap my stock E350 4600 pound front coil springs with lower-rated ones designed for an E150. I strongly advise to learn from my results before taking any such action with your own 2350s.
Regarding your rear suspension, a truck suspension shop should be able to take the weight numbers you provide and determine how many rear leaf springs to remove to decrease the amount of load margin to get you to the 500-750 number.
In my case, I wish I could add one more leaf spring per rear corner to increase my rear axle capability and lift it up to rid our slight rear end sag. I can't add any leaf springs because the extra height will prevent the rig from clearing our already tight garage door clearance.