Hopefully someone will chime in, but I think PCs with the bathroom across the back wall have a pocket door in the center isle. I imagine they leave the door open to allow cold a/c into the bath.
Leaving the door open on a 2350 is different because it swings into the room, not hidden in the wall.
As far as how many a/c units is concerned, it is surely nice to have two for a variety of reasons. Since they all run loudly, it is nice to turn off the one where you are hanging out at the time. Run the living room a/c unit when sleeping, and run the bedroom unit during the day. If you are in extreme heat, then run both full blast to maintain a more comfortable temperature.
Having two a/c units in a 2551 and shorter is unheard of. I think there are a few 2552s with 2 a/c units. Hopefully someone with a 2552 will have a lot to share. Bigger than a 2552 would surely benefit having 2 a/c units.
Of coarse, if you never camp in hot climates, that changes everything.
I wonder how people handle "power" with 2 a/c units. I don't think the standard 4000 watt Onan generator will support both running at the same time. I wonder if a larger generator fits in the PC provided space.