We have an older 2007 2350 model. Like Barry-Sue says, the handling of the 2350 is typically poor right from the factory. I would imagine the 2100 would have similar handling concerns. There are a couple factors as to why.
1) - The distance between front and rear wheels called the wheel base is too little when considering the large amount of house over-hanging behind the rear wheels.
2) - The 2100 and 2350 are built on the lighter duty E350. The 2551 and larger PCs are built on the E450 that has a heavier duty suspension.
I would not let these comments discourage you from considering a 2100 or 2350. Just be aware of this. If you find the handling acceptable, then there is nothing more to do. If it handles too poorly for comfort, then consider investing in a few suspension upgrades.
I hate to share what we had done because it scares people. We went all-out doing everything that came recommended by our local motor home suspension shop. Since we had the work done, our 2350 handles nice and tight, firmly planted on the road like an SUV, instead of a drunken sailer. And the ride is not harsh either. We love it for both comfort and safety. My thinking is that if it prevents just one accident, it paid for itself at least 100 fold in saving the PC, the tow vehicle, us the occupants, and anyone else around us who might be involved.
Here are the details on what we had the shop do for us.
1) - Added a heavy duty rear sway bar.
E350s made prior to 2008 did not come with any kind of rear sway bar.
2) - Replaced the front sway bar with a heavy duty bar.
The Ford stock bar is the same one used in the light duty E150
3) - Replaced the 4 Ford shocks with Koni-RV adjustable shocks, set to the stiffest of the 3 settings
Today I recommend Koni-FSDs, offered only through Henderson Line-Up.
The FSD shocks are designed for class-A and Super-C motor homes.
I understand Henderson replaces the 3/4" mounting bushing in each shock with a 5/8" to fit an E350/E450
The stock Ford shocks are the same used on an E250 van.
4) - Replaced the front steering stabilizer with a heavy duty one
The stock Ford one is the same used on an E150 van
5) - Added a rear Trac bar.
This eliminates horizonal side-to-side motion of the rear end, referred to as tail wagging
Especially benefitial when towing.
6) - A front wheel alignment
The camber was so far out of whack that the shop used special off-set bushings to correct it
Such bushing kits are available as this is a very common problem with many brand motor homes.
We had our local shop order and install everything which was not the cheapest way of handling this. It cost us $3900 but worth every penny. Since the work was done in late mid 2007, we can take on hair-pin turns on scenic byways with the greatest of confidence keeping all 6 tires firmly planted on the road for good control and braking while in the turns. The rig hardly leans in the turns. Also on the open road when semi-trucks pass and when gusting cross winds are present, driving is still a casual one hand-on-the-wheel experience. Driver fatique is greatly reduced which is another comfort and safety factor.