My own two cents -
Many years ago, when moving a friend, we had rented an E-series cutaway moving truck. Had to have been the then-E450 chassis based on box size alone, and was advertised to have "air-ride" suspension.
Under a full load (including an upright piano), handled quite well, full or empty on local streets under 45 MPH, and was quite peppy, more or less keeping up, and competitive with, ordinary cars.
Anyway, we were quite pressed for time in getting to a store before it closed, and with a full load that included a number of mirrored and glassed furniture pieces resting perpendicularly and directly on the load floor (hey, it was the 80's LOL!), I mindlessly blew into the parking lot at about 40 MPH.
At that time, tall and sharply contoured speed bumps were the order of the day in the malls of the past! As I rapidly approached the first bump, I winced - the certain destruction of all delicated items aboard certainly doomed to my carelessness, yet sharp braking would have resulted in equal destruction of our load! Yet we flew over it with narry a jar nor bobble! Wow! This "air-ride" was great! We proceeded onwards at 40 MPH! It was truly amazing!
For those Francophiles among us, just as if you ran over a cow with a Citroen auto. Wow!
Don't know about RV's or trucks, but it seems any autos with air suspension years ago were subject to considerable maintenance requirements and cost.
Were superior ride quality and handling a must, along with many miles driven per year, I can say it would probably be worth the cost of air suspension for me. You'd never spill a drop of gin and tonic, and you ladies could probably apply make-up underway.
I would decide it to be unaffordable for myself - but for those of you who can, do look into it. Miracles are available.