John regularly lifts the front tires off the ground. Many campsites slope away and down to the front for drainage. We only lifted the rear tires once... and rolled forward off the jacks. It was a serious HOLY COW moment and we've never done that again. I think part of our problem is we've never calibrated the jacks. I read somewhere you should do that. John is an engineer and if the control pad on the jacks says he needs to lift the front, he lifts it unless I can pull out a level and prove the control panel wrong (and after a mild discussion - NO, we are NOT level - it's lying to you again, look at the tilt - sometimes my argument works, sometimes not. Engineers go by the numbers.)
We don't mind mild tilt but there are some areas with enough tilt that the fridge goes into fault mode (like the driveway where we are staying). We have to get level enough for safe operation of the fridge. We've camped tilted to the side badly enough once that I had to hang on to prevent myself rolling off the side of the bed (we were not able to use jacks where we were). This does not make for a restful night.
We love having jacks and use them most nights but John really covets jacks that can be leveled individually as we frequently have one low corner and it's tricky raising and lowering front then side then back then side to get one jack lower than the others. It's all personal preference though.