As I understand the battery thing, there is no difference in performance between a pair of 6 volt and a pair of 12 volt assuming they are constructed the same and contain the same amount of lead and thickness of plates. But that is the issue, most 6 volts are designed for deep cycle applications like golf carts and most, but not all, 12 volts deep cycle are more a compromise. There are (I have been told) 12 volt deep cycle ones that are just as good as the 6 volt, but they are harder to find and cost more. So bottom line, in general a pair of 6 volt batteries is going to be better for this application, and likely cost less than the equivalent 12 volt ones.
I suspect the problem for most RV'ers having early battery failure is the old style, single stage converter still being used. If plugged in for any length of time these will boil your batteries, and then it is all down hill from there. Used in a normal 'camping' scenario where you are using power as fast as you put it back this is not a problem (usually) but if plugged in for a long time the batteries get boiled and then with each consecutive charge cycle it gets easier to boil them and the cycle spirals down into premature failure.
Having a battery monitor and modern 3 stage charger will go a long way to prevent this and extend the life of your batteries. I wish I had thought this through when I ordered as I would have swapped out the converter for a newer one. I will likely do that as soon as I get the rig back home. Cost is maybe $200 and that is far less than a new pair of 6 volt AGMs.