We drove that road a couple years ago in our 2551 towing a Wrangler. We went down into Death Valley on 190 and there was no problem with the road, I don't know how it is to go uphill on that road. We left to the east on 178 to Pahrump, NV and it was an uphill climb with sharp turns and a temp of 113F, the PC made it out with no problem. I decided that I should turn off the AC to keep the engine temp down in that heat going uphill and it worked fine, no indication of overheating. Based on this experience, I personally would not hesitate to go out hwy 190.
I thought it would be a good idea to turn on the generator and run the coach AC to keep us cool, it worked great for a bit until I hit the steepest part turning a sharp corner and the generator went off. Apparently the fuel in the tank was below half and it sloshed around enough to suck air in the generator pick up tube which is at about 1/4 tank level. Fortunately the outside temp cooled off quickly as we climbed out of the valley.
Bob