I read the E450 will not drop away when the Transit debuts. But I wonder if the E350 will continue to be around if the Transit and E350 host the same capabilities. I saw the new Transit van, a locked up prototype, shown at the Chicago auto show. It's no small van in physical size, a close cousin of the Sprinter. Assuming the power train is capable, and a DRW (Duel Rear Wheel) version becomes available, it could replace the E350. If Ford drops the E350, then PCs currently constructed on the E350 may be adjusted to fit a Transit.
I hope Ford would retain the stance of an E350, not modelled after a Sprinter with the rear wheels set inside so far. I am turned off by the tires inset like that, seemingly carried over from Europe for their narrow streets.