R and C
I need to agree with ragoodsp, you will find many opinions on this subject. There are older discussions discussing this very subject. But for my 2 cents, I have owned both the MB sprinter under a 2350 and my current 2552 with the Ford 450. I have added suspensions upgrades to the ford as ragoodsp did. My preference for ride and handling is the 450. Sounds like ragoodsp had about the same mileage as I did in the MB and in the 450 I get 9-10 mpg. It's still fairly new and I've been driving about 65mph on the highway most of the time. I think I could probably get slightly better if I ease up a bit but this year I was making many golf buddy trips and we needed to get to the courses

. Still it will take many miles to make up the difference in gas cost vs the extra you pay for the sprinter.
Jim